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About me I am a Junior Scientist at the Kerala State Council for Science, Technology and Environment (KSCSTE) with research expertise in marine biotechnology, microbial natural products, and bioactive compound discovery from marine and freshwater organisms. My work focuses on the isolation and characterization of bioactive metabolites and exopolysaccharides from seaweed- and microalgae-associated bacteria, with potential applications in pharmaceuticals, cosmeceuticals, and nutraceuticals. My research integrates microbial biotechnology, natural product chemistry, and molecular biology to identify novel compounds with antimicrobial, antioxidant, anti-inflammatory, wound-healing, and UV-protective properties. I have extensive experience in microbial isolation, genome mining for biosynthetic gene clusters, chromatographic and spectroscopic characterization, and bioactivity evaluation using in vitro and in vivo models. Schemes & programmes (including external funded Programmes): Academic Qualifications: PhD Subject: Marine Sciences Title: Development of Polyketide Class of Compounds from Seaweed-associated Firmicutes and their Pharmacological Potential Year: 2023 Institution: Central Marine Fisheries Research Institute, University: Cochin University of Science and Technology Professional Experience/ Academic Positions: Broad area Peptide Chemistry Peptide Synthesis Protein Folding Details of ongoing and completed project Best cited Publications Switch peptides in statu nascendi: induction of conformational transitions relevant to degenerative diseases; Manfred Mutter, Arunan Chandravarkar, Christine Boyat, John Lopez, Sonia Dos Santos, Bhubaneswar Mandal, Richard Mimna, Karine Murat, Luc Patiny, Lydiane Saucède, Gabriele Tuchscherer; Angewandte Chemie International Edition 43 (32), 4172-4178 Switch-peptides: controlling self-assembly of amyloid β-derived peptides in vitro by consecutive triggering of acyl migrations; Sonia Dos Santos, Arunan Chandravarkar, Bhubaneswar Mandal, Richard Mimna, Karine Murat, Lydiane Saucède, Patricia Tella, Gabriele Tuchscherer, Manfred Mutter; Journal of the American Chemical Society 127 (34), 11888-11889. Kannurin, a novel lipopeptide from Bacillus cereus strain AK1: isolation, structural evaluation, and antifungal activities; K Ajesh, S Sudarslal, C Arunan, K Sreejith; Journal of applied microbiology 115 (6), 1287-1296 CSIR Research Fellowship, Swiss National Science Foundation Fellowship for Post-doctoral studies. Young Scientist Award from STEC, Govt. of Kerala. Membership in Professional Bodies Kerala Academy of Science Magnetic Resonance Society- Kerala Ms. Lakshmi Project Fellow Ms. Rajila R.L Project Assistant Dr. C. Arunan Chief Scientist, 4th Floor Sasthra Bhavan, Pattom, Thiruvananthapuram-04 Email ID: carunan@gmail.com; carunan.kscste@kerala.gov.in Phone (Office/Mob):0471- 2548314
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